Hagiographical studies have seen significant advances in Franciscan scholarship over the last half a century with new critical editions of central texts being prepared. The fruits of this research have been made available in English translations, from the Omnibus of the Sources for the Life of St Francis to the publication of Francis of Assisi: Early Documents in three volumes with an excellent index at the turn of the new millennium. The examination of the life of Francis of Assisi is (...) now gravitating towards liturgical texts in order to gauge the image of the saint projected during the sacred liturgy in the Mass and the Divine Office. There is a growing realization that these liturgical texts did much to condition... (shrink)

Este artículo considera el tema de las tecnologías de representación de las ruralidades queer en el cine. Las autoras llevan a cabo un análisis pormenorizado de la representación de las disidencias sexuales y de género sostenidas en y a través de espacialidades rurales tomando como objeto de estudio tres piezas fílmicas producidas en el estado español durante las últimas dos décadas, a saber, Ander (2009), 80 Egunean (2010) y Elisa y Marcela (2018). A manera de conclusión, el artículo muestra las (...) tensiones entre dos marcos interpretativos desde los que afrontar los ensamblajes en que se relacionan las ruralidades y las disidencias sexuales y de género. Estos son el enfoque de las ruralidades urbanas que produce epistemologías de carácter identitariamente fuerte, y el enfoque de las ruralidades queer que permite leer las representaciones tomadas en cuenta como figuraciones posidentitarias y subversivas de la disidencia. (shrink)

We report the identification of a recurrent, 520-kb 16p12.1 microdeletion associated with childhood developmental delay. The microdeletion was detected in 20 of 11,873 cases compared with 2 of 8,540 controls and replicated in a second series of 22 of 9,254 cases compared with 6 of 6,299 controls. Most deletions were inherited, with carrier parents likely to manifest neuropsychiatric phenotypes compared to non-carrier parents. Probands were more likely to carry an additional large copy-number variant when compared to matched controls. The clinical (...) features of individuals with two mutations were distinct from and/or more severe than those of individuals carrying only the co-occurring mutation. Our data support a two-hit model in which the 16p12.1 microdeletion both predisposes to neuropsychiatric phenotypes as a single event and exacerbates neurodevelopmental phenotypes in association with other large deletions or duplications. Analysis of other microdeletions with variable expressivity indicates that this two-hit model might be more generally applicable to neuropsychiatric disease. © 2010 Nature America, Inc. All rights reserved. (shrink)

This book was translated from the French by Marco Pallis. It is divided into three parts: in The Tracks of Buddhism, Buddhism's Ally in Japan Shintö or the Way of the Gods, and Vistas of the Mahäyäna. The first has ten short essay chapters, Originality of Buddhism, Message and Messenger, Charity and Existence, The Question of Illusion, A Buddhist Eye on Science, Cosmological and Eschatological Viewpoints, More About Human Destinies--the Function of Mercy, What is Matter and Who is Mära?, Some (...) fallacies and facts concerning Buddhism, and Glimpses into Zen. These essays do not present the philosophical systems of Buddhism but rather attempt to give a picture of the spirit of Buddhism. The second part has three short essay chapters: Science, Myth, and the Meaning of Ancestors, Ethics and Mythology of Shinto, and The Noble Virtues: Some lessons of Shinto. The third part contains four essay chapters: Treasures of Buddhism, Mystery of the Bodhisattva, The Feminine Element in Mahayana, and Synthesis of the Päramitäs. Contrary to the trend of recent books which are attempting to differentiate the acceptances of the various schools within Buddhism, this book tends to stress similarities even with non-Buddhist Indian systems. It is best suited for those who would like to enter into the general spirit of Indian religions without necessarily concentrating on Buddhism.--P. J. H. (shrink)

Presentación inaugural. Semblanza de Suárez. Dos opúsculos inéditos y una carta auténtica. Por T. Andrés Marcos.--Suárez y el pensamiento inglés contemporáneo, por F. Elías de Tejada.--Suárez, maestro de metafisica para teólogos, por M. Solana.--Conceptos dinámicos en la metafisica de Suárez, por J. Iturrioz.--La igualdad jurídica según Suárez, por E. Elorduy.--El sentido de la realidad en la metafisica suareciana, por F. García Martínez.--Palabras de clausura, por N. Rodríguez Aniceto.

This is a well-written analysis of the interpreters and interpretations of the Buddhist nirvana from the West. The first chapter treats the West's encounters with Buddhism before 1800, Marco Polo, etc. The remainder of the book deals with the interpretations of nirvana by Eugène Burnouf, Friedrich Max Müller, James D'Alwis, Robert Caesar Childres, Schopenhauer, Wagner, Nietzsche, Hermann Oldenberg, the Rhys Davidses, La Vallée Poussin, and Stcherbatsky. The author's own opinion is given in a few pages at the end of the (...) book; however, his opinion is not so much an exposition of nirvana but a short essay on the methodology of a study of nirvana. He quotes Richard Robinson to bring home his point that this long array of scholars could not forsake their cultural bias and that one needs therefore to approach non-Western ideas from the inside of a non-Western culture. Welbon's intention is to present an outline of the history of Western discussions on the meaning of the Buddhist nirvana. His research is thorough; his presentation is clear; this is a chronicle of heroic but club-footed attempts to learn about a non-Western idea. The book should be read by all aspiring Buddhologists, for it will convince them of the absolute necessity of learning the language of a Buddhist culture and of searching out qualified native informants. Its value for non-Buddhologists is not to learn more about nirvana but to learn the history of this burgeoning study. Welbon has admirably succeeded in his aim; he has concisely presented Western opinion on nirvana up to World War II.--P. J. H. (shrink)

Two well-known ancient witnesses report that Aristophanes of Byzantium was responsible for the arrangement of Pindar's poems into seventeen book-rolls according to lyric genres. These witnesses form fr. 381 in the edition of Aristophanes’ fragments by W.J. Slater : Vit. Pind. P.Oxy. 2438.35–9 δ]ιῄρητα̣ι̣ δὲ α̣ὐ̣τ̣[ο]ῦ̣ τ̣[ὰ ποιήματα ὑπ’ Ἀριστοφάν]ους εἰς βιβλία ιζˊ· διθ̣[υ]ρά̣[μ]βων βˊ [προσοδίω]ν̣ βˊ παιάνων αˊ πα[ρ]θεν[εί]ων γ̣ˊ [ἐπινικίω]ν̣ δˊ ἐγκωμίων αˊ ἐν [ᾧ] κα̣ὶ [σκ]όλ̣[ια ±4 ὕμ]ν̣ων αˊ ὑ[π]ορχημάτων αˊ θρ̣[ήνων.| nisi aliter ind., omnia suppl. Lobel (...) | 2 Ἀριστοφάν]ους Lobel e Vit. Pind. Vat. | 3 ἐν [ᾧ] κα̣ὶ [σκ]όλ̣[ια …. de Kreij : ἐν [ᾧ] κ[αὶ σκόλιά τινα vel ἐν [ᾧ] κ[αὶ σκόλιά ἐστι Gallo : ἐν [ᾧ] καὶ [παροίνια D'Alessio | 4 αˊ post θρ̣[ήνων coni. edd., fort. recte; an θρ̣[- βˊ?Vit. Pind. Vat. page 7.14–17 Dr. ὁ δὲ ἐπινίκιος οὗ ἡ ἀρχὴ “Ἄριστον μὲν ὕδωρ” προτέτακται ὑπὸ Ἀριστοφάνους τοῦ συντάξαντος τὰ Πινδαρικὰ διὰ τὸ περιέχειν τοῦ ἀγῶνος ἐγκώμιον καὶ τὰ περὶ τοῦ Πέλοπος, ὃς πρῶτος ἐν ῎Ηλιδι ἠγωνίσατο.A much-debated question is whether the order of the poems attested by the papyrus can be credited to Aristophanes, since an ordering principle is apparently not to be found in the list transmitted by it. Moreover, there are some disagreements with the list of Pindar's works transmitted by the Vita Ambrosiana, which is generally deemed the most authoritative catalogue of the poet's corpus, on account of its well-recognized criterion of classification: the poems are divided between those for gods and those for men, and both of these categories of songs are arranged from the most general to the most specific. This catalogue has been thought to reproduce the order established by Aristophanes in his edition of Pindar. (shrink)

BackgroundThe ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are widely endorsed but compliance is limited. We sought to determine whether journal-requested completion of an ARRIVE checklist improves full compliance with the guidelines.MethodsIn a randomised controlled trial, manuscripts reporting in vivo animal research submitted to PLOS ONE (March–June 2015) were randomly allocated to either requested completion of an ARRIVE checklist or current standard practice. Authors, academic editors, and peer reviewers were blinded to group allocation. Trained reviewers performed outcome adjudication (...) in duplicate by assessing manuscripts against an operationalised version of the ARRIVE guidelines that consists 108 items. Our primary outcome was the between-group differences in the proportion of manuscripts meeting all ARRIVE guideline checklist subitems.ResultsWe randomised 1689 manuscripts (control: n = 844, intervention: n = 845), of which 1269 were sent for peer review and 762 (control: n = 340; intervention: n = 332) accepted for publication. No manuscript in either group achieved full compliance with the ARRIVE checklist. Details of animal husbandry (ARRIVE subitem 9b) was the only subitem to show improvements in reporting, with the proportion of compliant manuscripts rising from 52.1 to 74.1% (X2 = 34.0, df = 1, p = 2.1 × 10−7) in the control and intervention groups, respectively.ConclusionsThese results suggest that altering the editorial process to include requests for a completed ARRIVE checklist is not enough to improve compliance with the ARRIVE guidelines. Other approaches, such as more stringent editorial policies or a targeted approach on key quality items, may promote improvements in reporting. (shrink)

Albert and De Ruiter provide an introduction to the Conversation Analytic approach to ‘repair’: the ways in which people detect and deal with troubles in speaking, hearing and understanding in conversation. They explain the basic turn‐taking structures involved, provide examples, explain recent developments in the field and highlight some important points of contact and contrast with work in the Cognitive Sciences.

1. The Commentariolum Petitionis is not in the Codex Mediceus of Cicero's correspondence with his brother Quintus, but it appears at the end of the letters to Quintus in the other manuscripts. It starts in the normal manner of a letter and is, or purports to be, a collection of tips on canvassing set in the particular context of M. Cicero's consular candidature in 64: a composition of his brother Quintus. It is printed as no. 12 in Tyrrell and Purser's (...) collection of Cicero's Letters. (shrink)